Drug Detail

Information about Semaxanib

Generic Name	Semaxanib
IND	SU5416
Brand Name (US)
Manufacturer	Sugen
Drug Type	Tyrosine Kinase Inhibitor
Delivery
Approval Status	Discontinued
Indications
Overall Strategy	GIST Tumor Based
Strategy	Block tumor blood vessel growth
Drug Category	VEGFR inhibitor (TKI)

SU5416 was an early TKI developed by Sugen. It was discontinued as other, more potent TKI's were developed, especially SU11248 which would eventually be the 2nd drug approved for GIST.