Drug Detail

Information about Imatinib + MEK162

Generic Name	Imatinib + MEK162
IND
Brand Name (US)
Manufacturer
Drug Type
Delivery	Oral
Approval Status
Indications
Overall Strategy	KIT Protein Based + Oncogenic Signal Path Based
Strategy	Block KIT + Block KIT Signal Path
Drug Category	KIT/PDGFRA inhibitor + MEK inhibitor

Links
Trials of this drug
	MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)

Trial results
	Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors (GIST)

	Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor