Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
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259 drugs found

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Targets
Lenvima
Eisai Co.
KIT
PDGFRa
VEGFR1
VEGFR2
VEGFR3
RET
FGFR1
FGFR2
FGFR3
FGFR4
Mundipharma-EDO Gmbh
Histone-deacetylase
Edo
EntreMed
Aurora Kinase A
Aurora Kinase B
VEGFR2
KIT
FGFR1
Yondelis
Johnson & Johnson
Istodax
Gloucester Pharmaceuticals
HDAC
Genentech
Erivedge
Genentech
SMO (smoothened receptor)
Piramed
PI3K Class 1
Genentech
PI3K
MEK
Genentech/Exelixis
MEK
Genentech
Genentech/Piramed Ltd.
PI3K
mTOR
GSK
IGF1R
Mekinist
GlaxoSmithKline
MEK1
MEK2
TAFINLAR
GlaxoSmithKline
BRAF
BRAF V600E
BRAF V600K
Votrient
GlaxoSmithKline
KIT
VEGFR-1, 2, 3
PDGFRA
PDGFRB
Itk
LCK
c-Fms
FGFR -1 and -3
Aventis
Ascentage Pharma
Bcr-Abl
KIT
Novartis/Vernalis
Hsp90
Stanford University
CD47
IDRx, Inc.
KIT V654A
PDGFRa V651D
Novartis
KIT (imatinib)
FGFR
Novartis + Bristol Myers-Squibb
CTLA-4 (ipilimumab)
KIT (imatinib)
Gleevec + PEG-Intron
Novartis, Schering
KIT
PDGFRA
Bcr-Abl
Gleevec
Novartis
KIT
Bcr-Abl
PDGFRA
PKC alpha
PKC beta
PKC gamma
VEGFR
FGFR
FLT3
Gleevec, Tasigna
Novartis + Novartis
Both have similar targets
KIT
Bcr-abl
PDGFRA
PDGFRB
Novartis
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
PI3K (BKM120)
ImClone
PDGFRA
ImClone
IGF-1R
ImClone
IGF-1R (IMC-A12)
mTOR (CCI-779)
Inhibrx, Inc.
DR5 (Death receptor 5)
Inhibrx, Inc.
DR5 (Death receptor 5)
DR5 (Death receptor 5)
Incyte
Incyte
IDO1
Insmed
IGF1R
Infinity
HSP90
Infinity
HSP90
Sprycel + Yervoy
Bristol-Myers Squibb (both)
CTLA-4 (ipilimumab)
KIT (dasatinib)
PDGFRB (dasatinib)
bcr-abl (dasatinib)
SCR (dasatinib)
EPHA2 (dasatinib)
LCK (dasatinib)
YES (dasatinib)
FYN (dasatinib)
ISA Pharmaceuticals
MSI-H
dMMR
Kura Oncology Inc
Menie-MLL
Keryx
AKT
Kolltan
Kit
Kirin
IGF-1R
Novartis
Farydak
Novartis
HDAC
Novartis
Novartis
KIT
Loxo Oncology
TrkA
TrkB
TrkC
NTRK
Merck
ATR
Yervoy
Bristol-Myers Squibb
CTLA-4
MedImmune LLC
IGF1
IGF2
IGF-1R (indirectly)
IR-A (indirectly)
Medimmune
PD-L1
B7H1
Novartis
MEK 1/2
Novartis
PI3K Class 1A
MEK 1/2
Merck
IGF1R
Keytruda
Merck
PD-1
Keytruda + Cyclophosphamide
PD-1
CD4+ Treg
CD8+ Treg
HIF2A
Zolinza
Merck
HDAC
Millennium
KIT
FLT3
PDGFRB
PDGFRA (possible)
Millenium
KIT
FLT3
PDGFRA
Hoffman-La Roche
PD-L1
Bristol-Myers Squibb
PRMT5
EMD Serono
EMD Serono
Ningbo Newbay
KIT
PDGFRA
Genentech
IDO1
Novelty Nobility
KIT
Novartis
IGF1R
Sandostatin
Novartis
SSTR
OSI
IGF1R
IR (insulin receptor)
OSI
KIT
VEGFR
Phoenix Biotechnology, Inc.
α-3 subunit of Na-K ATPase pump
Pfizer
Ibrance
Pfizer
Cdk4
Cdk6
Novartis
PD-1
Campostar
Pfizer
Pfizer
Pfizer
Novartis
PKC alpha
KIT
PDGFRA
PDGFRA (D842V)
VEGFR1
VEGFR2
VEGFR3
FLT3
PKC beta
PKC gamma
FGFR
Plexxicon
KIT
FLT3
Fms/CSF-1
CSF-1R
Zelboraf
Plexxicon
BRAF V600E
Cogent Biosciences
KIT
FLT3
CSF-1R
PharmaMar
Tubulin
Velcade
Millennium
26S proteasome
Peloton
HIF-2a
Novartis
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRB
Oncothyreon
HIF-1α
Oncothyreon
PI3K Class I
Topo/Target A/S
Hoffmann-La Roche
IGF1R
Afinitor/Certican
Novartis
mTOR
Roche
MDM2
Genentech/Amgen
DR4 (Death receptor 4)
DR5 (Death receptor 5)
Hoffman-La Roche
gama-secretase
Ignyta
TrkA
TrkB
TrkC
ROS1
ALK
NTRK
EMD Serono
Schering-Plough
IGF1R
Semafore
PI3K Class 1A
DNA-PK
mTOR
Polo-like 1 kinases
PIM1
CK2
Astex Pharmaceuticals
cKit
PDGFRa
VEGFR2
VEGFR3
FLT1
FLT3
Rapamune
Wyeth
mTOR
Serenex
HSP90
Novartis
SST-1
SST-2
SST-3
SST-5
Somatostatin receptors (SST-1, SST-2, SST-3, SST-5)
Synta
HSP90
Gleevec + Genasense
Novartis + Genta
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (imatinib)
Bcl-2 (Genasense)
Gleevec + Proleukin
Novartis + Novartis
KIT (Gleevec)
Bcr-Abl (imatinib)
PDGFRA (Gleevec)
Interleukin-2 (IL-2)
Gleevec
Novartis
KIT
bcr-abl
abl
PDGFRA
PDGFRB
Gleevec + AT13387
Astex Therapeutics
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
Hsp90 (AT13387)
Gleevec + Avastin
Novartis and Genentech
KIT (imatinib)
VEGFR (bevacizumab)
PDGFRA (imatinib)
PDGFRB (imatinib)
Bcr-Abl (imatinib)
Gleevec
Novartis + Keryx
KIT
AKT
PDGFRA
Bcr-Abl
Gleevec
Novartis + Novartis
HDAC
KIT
PDGFRA
PDGFRB
Bcr-Abl
Gleevec + Afinitor
Novartis, Novartis
KIT
PDGFRA
Bcr-Abl
mTOR

259 drugs found

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